Why does my sertraline smell like vanilla

Objective: To evaluate the efficacy and safety of high-dose sertraline for patients with obsessive-compulsive disorder (OCD) who failed to respond to standard sertraline acute treatment. Method: Sixty-six nonresponders to 16 weeks of sertraline treatment who met DSM-III-R criteria for current OCD were randomly assigned, in a double-blind continuation phase of a multicenter trial, either to ...

indigestion, nausea, diarrhea, loss of appetite; nose bleeds; increased sweating; tiredness, sleep problems, insomnia; anxiety; loss of bladder control; tremors or agitation; or. sexual problems. This is not a complete list …By tammy1234. Last reply 3 months ago. 22. Patient Forums for Sertraline. Part of the Mental health category. Symptom, treatment and advice from community members.In fact, the medication’s labeling recommends avoiding alcohol. Combining alcohol with sertraline can worsen side effects. Symptoms can include excessive drowsiness or dizziness. On top of that, worsening depression and sleep changes are also possible. It’s best to completely avoid alcohol while taking sertraline.I found a few case reports addressing observed cross-reaction between SSRIs. Kkairkar (1) presented a patient with a macular rash following the use of sertraline (Zoloft).The rash resolved within 2 days of its discontinuation and oral therapy with diphenhydramine and betamethasone. Ten days later the patient was started on paroxetine (Paxil).By increasing serotonin production, Zoloft and similar drugs work to counteract depression. In order to understand the adverse reactions that can occur when mixing sertraline with marijuana, you first need to understand the side effects that can occur with Zoloft alone: - Insomnia. - Drowsiness. - Dizziness. - Agitation. - Indigestion ...Sertraline Pill Images. Note: Multiple pictures are displayed for those medicines available in different strengths, marketed under different brand names and for medicines manufactured by different pharmaceutical companies. Multi-ingredient medications may also be listed when applicable. What does Sertraline hydrochloride look like?Antidepressants and REM sleep. Another factor may be the potential impact of antidepressants on REM (rapid eye movement) sleep. Most dreams occur during this restorative phase of sleep, and it is thought to play a role in learning, memory and mood. "There's evidence that SSRIs impact rapid eye movement (REM) sleep, which is when most dreams ...

Severe Side Effects. When first starting Zoloft or after changing the dosage, report any of the following side effects to a healthcare provider immediately: Allergic reaction symptoms such as hives, rash, difficulty swallowing or breathing, severe dizziness, and swelling of the face, mouth, throat, or tongue.Grapefruit Juice. If you recently started adding a glass of grapefruit juice at breakfast or having the fruit as a mid-morning snack and you feel like your antidepressant isn't working, the dietary change could be the problem. Some antidepressants, like BuSpar and Zoloft, can't be taken with grapefruit or grapefruit juice because it will ...Zoloft is the brand name of a generic medication called s ertraline, which belongs to a group of drugs called selective serotonin reuptake inhibitors (SSRIs). SSRIs like Zoloft are antidepressants that work by increasing levels of serotonin in the brain. Zoloft is approved by the Food and Drug Administration (FDA) to treat the following conditions:Review. Depression and the heart. In the coming decade, depression may become the single largest contributor to medical illness around the world [].Heart disease is the leading cause of death on the planet, while CAD and depression are the major issues leading to long-term disability [5,7].SSRIs are the most frequently used antidepressants …The new vanilla coating on Zoloft pills is disgusting. I picked up a refill for my prescription today and took that day's dose from the new bottle. I noticed a sweet, vanilla-like smell and taste to the pills. Not a good kind of vanilla, but that nasty artificially manufactured vanilla smell that seriously makes me sick to my stomach.3 Potentially Dangerous Zoloft-Marijuana Interactions. 1. Higher Risk of a Bad Reaction to Zoloft. Cannabis has been shown to inhibit liver enzymes needed to metabolize Zoloft. This means the body doesn’t disperse and eliminate Zoloft like it should, leaving a higher-than-normal level of Zoloft in the bloodstream.Nov 6, 2022 · How would you describe the smell of vanilla? Vanilla has a sweet, rich, syrupy scent that exudes warmth in a uniquely alluring way. It cannot be compared to any other scent, and that’s part of its charm. Ironically, vanilla beans grow in an orchid-like plant along with flowers that have absolutely no scent.

Location. Potters Bar. Country. 10 Nov 2018. #7. NotSoNewboy said: The use of some flexible tap connectors can give a peculiar smell to hot water as the 'rubber' liner decomposes when heated. Agreed. I was thinking of asking if any other plumbing works may have been done recently, ie new taps!I emailed the manufacturer and got this really irritating response, but I guess at least we know it's on purpose and safe: The product is safe for use as we have recently implemented the flavored coating (Vanilla flavor) in the subject product and hence the sweet smell is due to the sameSymptoms can resolve sooner if you go back on your medication or take a new, similar antidepressant. Besides "brain zaps," antidepressant discontinuation syndrome can cause: Flu-type symptoms, such as feeling overheated and exhausted, and having headaches and muscle aches. Trouble sleeping, including nightmares. Nausea and vomiting.I received a free sample of Versace Eros and it actually works in my favor. The vanilla is amplified and it doesn't smell like a dude. But there's enough other scents to keep it from being boring or overly sweet. Also DG Light Blue for women smelled like musty butt on me. Super weird.

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I believe Sertraline in the US comes in tablet form which could be why theirs smell like vanilla? I'm not sure of any capsule that has a particular smell except maybe dutasteride. Cephalexin and metformin are usually awful in most brands but I believe one of the cephalexin brands (apo?) doesn't smell bad.Review. Depression and the heart. In the coming decade, depression may become the single largest contributor to medical illness around the world [].Heart disease is the leading cause of death on the planet, while CAD and depression are the major issues leading to long-term disability [5,7].SSRIs are the most frequently used antidepressants among the more than twenty different drugs available ...Zoloft is a brand (trade) name for sertraline. Sertraline is a medicine that may be used in the treatment of depression and other mood disorders. Experts believe Zoloft's (sertraline's) effects are due to its ability to rebalance chemicals in the brain, such as serotonin, that appear imbalanced in people with anxiety, depression, and other ...Jasmine lends a floral scent that is rich and sweet. To some, jasmine alone is almost too sweet of an aroma. However, when combined with other scents, it is just the right touch. Jasmine is also considered very sensual. In fact, jasmine is often described as being intoxicating and even exotic.

Why does Zoloft smell and taste like a vanilla milkshake? I mean really it does lol comments sorted by Best Top New Controversial Q&A Add a Comment AutoModerator • Additional comment actions. If this submission above is not a random thought, please report it. ...difficulty having an orgasm. dry mouth, and. weight loss. Tell your doctor if you have serious side effects of Zoloft including: very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, feeling like you might pass out; agitation, hallucinations, fever, overactive reflexes, tremors;Bij (jong)volwassenen zijn de serotonineheropnameremmers (SSRI’s) citalopram, escitalopram, fluoxetine en sertraline voorkeursmiddelen; bij ouderen zijn dit citalopram of sertraline. Switch bij onvoldoende of geen respons naar een andere SSRI van voorkeur. Bij goede respons de behandeling ten minste 6 maanden (ten minste 1 jaar bij recidief ...Jun 13, 2023 · Sertraline is used in the treatment of Depression, Post traumatic stress disorder, Obsessive-compulsive disorder, Panic disorder, Premenstrual dysphoric disorder, Anxiety, Premenstrual syndrome (PMS). View Sertraline’s uses, side-effects, drug interactions, expert advice and user FAQs only on 1mg.com. Sertraline is a widely used selective serotonin reuptake inhibitor (SSRI) that increases extracellular dopamine concentrations in the nucleus accumbens and striatum (Kitaichi et al., 2010). For these reasons, we sought to assess low-dose combined OLA and sertraline as novel clinical treatment strategies to reduce negative and depressive ...The recommended initial dosage and maximum ZOLOFT dosage in patients with MDD, OCD, PD, PTSD, and SAD are displayed in Table 1 below. A dosage of 25 mg or 50 mg per day is the initial therapeutic dosage. 50 mg per day increments once a week, depending on tolerability, up to a maximum of 200 mg per day.Typically labeled as "vanilla essence," this artificial vanilla is usually derived from, uh, less-than-organic material (like petroleum). While it mimics vanilla's smell, many would argue that it doesn't come close to capturing all of the complex floral and woodsy notes that result from the myriad of other flavor compounds in true vanilla.The results of the in vivo study appeared to be consistent with the in vitro findings, in that mean (+/- SD) serum sertraline trough levels increased significantly from 13.7+/-4.9 microg/L before to 20.2+/-4.4 microg/L (P = 0.047) after administration of grapefruit juice. Thus the in vitro study demonstrated that grapefruit juice can inhibit ...Summary. Sertraline (Zoloft) belongs to a class of antidepressants known as selective serotonin reuptake inhibitors (SSRIs). It can help manage mental health conditions, such as depression ...The recommended initial dosage and maximum ZOLOFT dosage in patients with MDD, OCD, PD, PTSD, and SAD are displayed in Table 1 below. A dosage of 25 mg or 50 mg per day is the initial therapeutic dosage. 50 mg per day increments once a week, depending on tolerability, up to a maximum of 200 mg per day.

15. Location. Florida. Lol that is funny... as I was reading I was trying to think of a scenario why a cat would smell like vanilla. I can imagine you checking all the cupboards and all that... as we usually did, every time we noticed that Tohey smelled unusual. Girl had a habit of climbing into the spice cupboard.

Sertraline is used in the treatment of Depression, Post traumatic stress disorder, Obsessive-compulsive disorder, Panic disorder, Premenstrual dysphoric disorder, Anxiety, Premenstrual syndrome (PMS). View Sertraline’s uses, side-effects, drug interactions, expert advice and user FAQs only on 1mg.com.It’s simple. Just add sugar. For 1 pint of extract, add up to a tablespoon of cane sugar; for a quart, add 2 tablespoons. This will soften the harsh smell of alcohol and initiate the aging process. This comes out to about 3% sugar in the extract. Within a week or two your extract will smell far more mellow.Sertraline should be administered once daily, either in the morning or evening. Sertraline tablet can be administered with or without food. Initial treatment. Depression and OCD. Sertraline treatment should be started at a dose of 50 mg/day. Panic Disorder, PTSD, and Social Anxiety Disorder . Therapy should be initiated at 25 mg/day.Jasmine lends a floral scent that is rich and sweet. To some, jasmine alone is almost too sweet of an aroma. However, when combined with other scents, it is just the right touch. Jasmine is also considered very sensual. In fact, jasmine is often described as being intoxicating and even exotic.Sertraline hydrochloride tablets may be taken with or without food. If you miss a dose of sertraline hydrochloride tablets, take the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and take your next dose at the regular time. Do not take two doses of sertraline hydrochloride tablets at the same ...3 Potentially Dangerous Zoloft-Marijuana Interactions. 1. Higher Risk of a Bad Reaction to Zoloft. Cannabis has been shown to inhibit liver enzymes needed to metabolize Zoloft. This means the body doesn’t disperse and eliminate Zoloft like it should, leaving a higher-than-normal level of Zoloft in the bloodstream.13 votes, 21 comments. Does anyone else's sertraline smell like frosting? Been on it for a year and this is the first batch that smells super sweet…lorraine70550 ClaraD. Posted 6 years ago. I have been on Sertraline 200 mg for at least 5 years and other antidepressants before that. I have gradually been coming off them. After 1 week reducing down50 mg each week. I have been off them now for over a week. My problem is feeling dizzy and having terrible nightmares.

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6. Sexual side effects. Sexual side effects can occur with sertraline. The most common sexual side effects are ejaculation problems, low sex drive (libido), and erectile dysfunction. Unlike the side effects mentioned previously, sexual side effects are less likely to improve over time.The study - conducted in nonhuman primates with brain structures and functions similar to those of humans - found that the antidepressant sertraline, a selective serotonin reuptake inhibitor (SSRI ...When taken as prescribed, Zoloft is not considered addictive. In fact, research shows it's tolerated well by most people who take it. It doesn't produce a euphoric high or cause cravings, like substances abused for recreational purposes do. That said, Zoloft addiction can still be a concern for many people, as it is possible to become ...00:00 - Why does my vanilla extract smell like alcohol?00:41 - What does pure vanilla extract smell like?01:15 - Why does my homemade vanilla tastes like alc...Zoloft (sertraline) is a serotonin reuptake inhibitor (SSRI) antidepressant used to treat depression, obsessive-compulsive disorder (OCD), panic disorder, post-traumatic stress disorder (PTSD), social anxiety disorder, and premenstrual dysphoric disorder (PMDD). Common side effects of Zoloft include sleepiness, nervousness, difficulty sleeping (insomnia), and others.Most adults can take sertraline. Children aged 6 to 17 years can also take sertraline, but only for obsessive compulsive disorder (OCD). If you have diabetes, sertraline can make it more difficult to keep your blood sugar stable. Your doctor may recommend that you monitor your blood sugar level more often for the first few weeks of treatment ... The usual dose of sertraline is 50mg a day in adults. But your doctor may start you on a lower dose, then increase it gradually to a maximum dose of 200mg a day. If you have liver problems, your doctor might give you a lower dose. The usual dose of sertraline for children aged 6 to 12 is 25mg a day, but this may be increased to 50mg a day after ... increased hunger. increased urination. loss of sense of smell. redness or other discoloration of the skin. severe sunburn. swelling of the breasts (in women) unexplained weight loss. unusual secretion of milk (in women) Other side effects not listed may also occur in some patients.Constipation is a common side effect of tricyclic antidepressants such as Elavil (amitriptyline) and Norpramin (desipramine). In addition to treating depression, tricyclic antidepressants may also be prescribed to treat anxiety or insomnia. Tricyclic antidepressants block the action of the neurotransmitter acetylcholine.3. We present another case of EPS associated with sertraline in which daily ratings were obtained using the Abnormal Involuntary Movement Scale. 4. This review and case report add to the small but growing literature suggesting that sertraline, like the other SSRI's may cause significant extrapyramidal side-effects.Apply the body mist on your clothes and your skin. This will make you smell good like a vanilla. 5. Perfumes with Vanilla Notes. When trying to smell like vanilla, always top up your skincare layering game with a perfume. Perfumes have a higher concentration and unlike body mists, they last longer and project good as well. ….

NI. Nicholas100 11 Oct 2020. I stopped sertraline about 6 weeks ago and switched to prozac--stopped prozac as strange bad tastes in mouth--- prozac can cause …Symptoms you may experience with sertraline withdrawal include: nausea. vomiting. dizziness. headaches. nightmares. flu-like symptoms. a prickling or tingling sensation on the skin. You may also experience symptoms that feel similar to those you experienced before you started to take sertraline.Review. Depression and the heart. In the coming decade, depression may become the single largest contributor to medical illness around the world [].Heart disease is the leading cause of death on the planet, while CAD and depression are the major issues leading to long-term disability [5,7].SSRIs are the most frequently used antidepressants …Try relaxing techniques. Relaxing techniques can surely calm a racing heart. You can try: Deep inhaling and exhaling. Yoga. Meditation. If you're working, try to take a break. Sit down comfortably and have a cup of your favourite tea.This increase in serotonin can have both positive and negative effects on the body. One of the positive effects is that sertraline can help alleviate symptoms of depression and anxiety. By increasing serotonin levels, it can improve mood and overall well-being. However, this increase in serotonin can also lead to side effects, including fatigue.ZOLOFT and other antidepressant medicines may increase suicidal thoughts or actions in some people 24 years of age and younger, especially within the first few months of treatment or when the dose is changed. Depression or other serious mental illnesses are the most important causes of suicidal thoughts or actions.Zoloft, a popular antidepressant medication, is known for its strong, distinctive smell that some describe as being similar to vanilla. This odor can be attributed to the inactive …Are you the proud owner of a Vanilla Gift Card? Whether it was given to you as a present or you purchased it for yourself, it’s essential to keep track of your balance. Before we d... Why does my sertraline smell like vanilla, Momentum's rubber straps are made for us by a family-owned company in Italy that has been making high quality rubber straps for generations. They discovered that adding a small amount of vanilla essence to the rubber compound "cancels out" the pungent natural rubber smell. While we do get an occasional customer who does not like the ..., Feb 9, 2023 · Usual Adult Dose for Panic Disorder. Initial dose: 25 mg orally once a day, increased after one week to 50 mg orally once a day. Maintenance dose: 50 to 200 mg orally once a day. Comments: Dose adjustments may be made at intervals of at least one week. These conditions generally required several months or longer of sustained pharmacological ... , Yes. The armpit odor is terrible and I've never had that problem before. I first noticed it a couple weeks ago. I was sitting in a meeting at a table and the people on either side of me moved. After the meeting I noticed the odor and couldn't believe how strong the odor was. 2., Here's what experts say about antidepressants and safely managing depression symptoms. It may be hard to believe that antidepressants can cause depression, but it could be true. The very reason ..., Sertraline is a medication that has been used to treat depression, obsessive-compulsive disorder, panic disorder, post-traumatic stress disorder, premenstrual dysphoric disorder (a severe form of premenstrual syndrome), and social phobia. Sertraline belongs to the class of antidepressants known as selective serotonin reuptake inhibitors (SSRIs ..., Serotonin syndrome—irritability, confusion, fast or irregular heartbeat, muscle stiffness, twitching muscles, sweating, high fever, seizure, chills, vomiting, diarrhea. Sudden eye pain or change in vision such as blurred vision, seeing halos around lights, vision loss. Thoughts of suicide or self-harm, worsening mood., Sertraline and other serotonin reuptake inhibitors possess tolerability advantages over tricyclic antidepressants. Sertraline has minimal anticholinergic activity, is essentially devoid of cardiovascular effects, has a wide therapeutic index and may be administered to elderly patients or those with underlying cardiovascular disorders. However ..., Not all antidepressants cause this shift, but the risk is present and it should be monitored. Additional side effects of Zoloft may include: sweating. sleepiness. insomnia. nausea. diarrhea ..., Abstract. Oxidation of active pharmaceutical ingredients is a common chemical degradation process occurring in solid dosage forms. The aim of this study was to investigate the tendency of various sertraline salts to oxidize in powder blends containing a basic additive. A different extent of conversion of each salt to the free base was observed ..., 6. Sexual side effects. Sexual side effects can occur with sertraline. The most common sexual side effects are ejaculation problems, low sex drive (libido), and erectile dysfunction. Unlike the side effects mentioned previously, sexual side effects are less likely to improve over time., Zoloft is an SSRI antidepressant medication that increases serotonin in the central nervous system. 1 If stopped abruptly, it can lead to withdrawal symptoms, including flu-like symptoms, nausea, anxiety, and hypersexuality. 2 To avoid these symptoms, patients should speak to their physician about a tapering dose of medication instead of ..., If the alcohol flavor dominates the flavor of the vanilla after two months, you might need to do some troubleshooting. Option one is to just wait it out. More time will result in a stronger flavor. To speed up the process, you could always add another vanilla bean pod and be sure to split the bean and scrape the seeds into the liquid., Applies to: sertraline and gabapentin. Treatment with sertraline may occasionally cause blood sodium levels to get too low, a condition known as hyponatremia, and using it with some anticonvulsants can increase that risk. In addition, sertraline can cause seizures in susceptible patients, which may reduce the effectiveness of medications that ..., The short answer is yes, but let's take a closer look at why and how to determine if your vanilla has gone bad. Pure vanilla extract is made by soaking vanilla beans in alcohol, which means that it has a long shelf life. However, over time, the flavor and aroma of the vanilla can start to deteriorate. If you notice that your vanilla has ..., Sertraline is a type of antidepressant called a selective serotonin reuptake inhibitor (SSRI). Research suggests that depression or low mood is more likely to occur when the brain doesn’t have enough serotonin. Serotonin (also called '5HT') is a naturally-occurring chemical messenger (or 'neurotransmitter') that has an important role in areas of the …, Review. Depression and the heart. In the coming decade, depression may become the single largest contributor to medical illness around the world [].Heart disease is the leading cause of death on the planet, while CAD and depression are the major issues leading to long-term disability [5,7].SSRIs are the most frequently used antidepressants …, Sertraline is a type of antidepressant known as a selective serotonin reuptake inhibitor (SSRI). Sertraline is used to treat a number of mental health conditions including depression, obsessive-compulsive disorder (OCD) , panic attacks, anxiety and post-traumatic stress disorder (PTSD). We don't know for certain, but researchers think that ..., Sopharso. ADMIN MOD. The smell of vanilla is the worst scent in the world. Other. Candles, air fresheners, body sprays etc are all vile. (Nothing against the taste though). Edit: Ok so I know there are technically worse smells but honestly I find the physical nausea I get from vanilla worse than I get from any "horrible" smells., Adults and teenagers—At first, 50 milligrams (mg) once a day, taken either in the morning or evening. Your doctor may adjust your dose as needed. However, the dose is usually not more than 200 mg per day. Children 6 to 12 years of age—At first, 25 mg once a day, taken either in the morning or evening., Summary. Sertraline (Zoloft) is an antidepressant drug. People who take Zoloft may have mild to severe side effects including nausea, heart palpitations, dizziness, and sleep problems. Zoloft ..., Not exactly what you want drugs to taste like. Little kids could get into them and may eat them if they taste good. This is from a CVS in California. My sertraline recently has had a weird sweet scent to it and leaves an aftertaste of candy in my mouth I find it really unsettling. Did they change…., MAOIs that may cause fatigue include: Emsam (selegiline) Marplan (isocarboxazid) Nardil (phenelzine) Parnate (tranylcypromine) Wellbutrin (bupropion) is another type of antidepressant known as a norepinephrine and dopamine reuptake inhibitor (NDRI). Wellbutrin may also cause fatigue., And with one in four of us affected yearly, it’s no surprise that the rise of medications, like sertraline, are at an all-time prescribing high. Between 2017 and 2018, 7.3 million UK adults were ..., Sertraline-induced diarrhoea - it can disrupt the normal balance of gut bacteria, leading to an increase in gas production and potentially smelly farts. A food allergy or sensitivity - consuming trigger foods can lead to digestive discomfort and increased gas production. This can result in smelly farts. Consuming large meals or overeating., Applies to: sertraline and gabapentin. Treatment with sertraline may occasionally cause blood sodium levels to get too low, a condition known as hyponatremia, and using it with some anticonvulsants can increase that risk. In addition, sertraline can cause seizures in susceptible patients, which may reduce the effectiveness of medications that ..., Jan 3, 2023 · Sertraline (Zoloft) is a medication prescribed to treat health conditions like anxiety and depression. It has many possible interactions. Examples of sertraline interactions include other antidepressants, phenytoin (Dilantin, Phenytek), and alcohol. It also interacts with blood thinners and medications that can affect heart rhythm. , Old. Q&A. N_Seven. • • Edited. So no one seems to have answered the question yet lol. It's a prodrug that has an ester side chain. The cleaving of the ester via hydrolysis results in something called RNH-8097 (literally not much on Google for that sucker) and diacetyl which smells like buttery popcorn to some degree., Sertraline is widely distributed, and its volume of distribution is estimated to be more than 20L/kg. 6 Post-mortem studies in humans have measured liver tissue concentrations of 3.9-20 mg/kg for sertraline and between 1.4 to 11 mg/kg for its active metabolite, N-desmethyl-sertraline (DMS). 7 Studies have also determined sertraline ..., A: Congrats on taking charge of your depression and feeling better. Yes, there are certain supplements that interfere with selective serotonin-reuptake inhibitors (SSRIs), and with serotonin and noradrenalin reuptake inhibitors (SNRIs) too. Serotonin is a neurotransmitter found in your gut, your blood and your nervous system., My mate was on them for about 4 years and they did bugger all for her until she was at the maximum dosage and even then it took about 6 weeks before she felt the cloud start to lift. She had a bout of severe depression. Im on then for anxiety and they have only just started kicking in for me on 150mg. Your doctor dont sound massively supportive ..., May 15, 2023 · Zoloft is a selective serotonin reuptake inhibitor (SSRI) that is also sold under the generic name sertraline. SSRIs prevent the reuptake of serotonin, allowing more serotonin to stay in the brain, which may improve your overall mood, sleep, and appetite while decreasing compulsive behaviors, symptoms of anxiety, and panic attacks. , In depression, sleep and appetite may get better soon after starting sertraline oral liquid. Other low mood signs may take up to 4 weeks to get better. This medicine may raise the chance of a broken bone. Talk with the doctor. This medicine may raise the chance of bleeding. Sometimes, bleeding can be life-threatening., Jan 11, 2024 · Jeffrey pine trees produce a similar aroma as ponderosa pines. It has commonly been described as smelling like vanilla or butterscotch; the scent has also been compared with apples, lemons, pineapple, and violets. The best way to enjoy the aroma is to break off a small shoot or bruise some pine needles, or by sniffing close to a fissure in the ...