Hydroxyzine and trazodone

difficulty with swallowing. dizziness. fainting. fast heartbeat. hives, itching, or skin rash. irregular or slow heart rate. puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue. trouble breathing. unusual tiredness or weakness.

Most frequently checked interactions. View interaction reports for chamomile and the medicines listed below. Major. Moderate. Minor. Unknown. 5-HTP (5-hydroxytryptophan) Alcohol (contained in alcoholic beverages) (ethanol) Aleve (naproxen)Dosage. Side Effects. Warnings and Interactions. Trazodone is an antidepressant in the serotonin modulators class of drugs. It is used to treat depression and works by increasing the action of serotonin in your brain. In addition to being used for managing depression, it can be used to treat insomnia and anxiety.Specifics of Trazodone. Trazodone is a serotonin receptor antagonist and reuptake inhibitor (SARI). The drug is believed to increase serotonergic activity in the central nervous system. It does this by inhibiting neuronal reuptake of serotonin and acting as an antagonist on the 5HT 2A subset of serotonin receptors. 1 By increasing serotonin …According to the experts, there are no harmful hydroxyzine interactions with caffeine. “There is no significant interaction between hydroxyzine and caffeine,” says Brandon Cometti, MD, a dermatologist at Roswell Skin Center in New Mexico. “Hydroxyzine is a sedating antihistamine, so it can make you drowsy, while caffeine is a …Comment: Barbiturates may increase adverse effects, including respiratory depression, produced by toxic doses of TCAs. With therapeutic doses of TCAs, barbiturates increase metabolism and decrease blood concentrations of TCAs. phenytoin. trazodone increases levels of phenytoin by unspecified interaction mechanism.Introversion isn't a flaw. In fact, introverts are powerful players in work and home life. Here, psychologist Alice Boyes shares how to use your natural personality traits towards ...Trazodone is an atypical antidepressant.It's FDA-approved to treat depression in adults, but it isn't a first-choice option.In addition, trazodone is sometimes prescribed off-label for difficulty sleeping (insomnia).This medication is taken by mouth, typically once or a few times a day, depending on your condition.Common side effects of …

US Pharm. 2010;35(11):HS-16-HS-21. A potentially lethal condition, serotonin syndrome (SS) is caused most often when certain antidepressant agents are taken concurrently with other drugs that modulate synaptic serotonin levels. 1,2 When patients take two or more antidepressants from different pharmacologic classes, drug-drug interactions may occur; these interactions may lead to potentially ...chlordiazePOXIDE hydrOXYzine. Applies to: chlordiazepoxide and Vistaril (hydroxyzine) Using chlordiazePOXIDE together with hydrOXYzine may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination.Patients with a history of heart disease or those who exceed the recommended dosage may experience unwanted reactions like heart palpitations. A recent study reported that out of 47,188 people who experienced unwanted reactions to hydroxyzine, about 393 (0.83%) had heart palpitations, implying that it’s a rare adverse reaction.Fear-extinction Medication - Fear-extinction medication works to inhibit the production of a protein called NMDA. Learn about NMDA and the uses for fear-extinction medication. Adve...Trazodone is an antidepressant medication commonly prescribed off-label for insomnia, with typical initial dosing at 25–100 mg before bedtime. In depressed patients, 150 mg is often the initial nocturnal dose. The dosage used in depression can be titrated upward, even up to 600 mg nightly, while closely observing blood pressure.

Using traZODone together with venlafaxine can increase the risk of a rare but serious condition called the serotonin syndrome, which may include symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea ... The treatment regimen generally included clonidine, hydroxyzine, trazodone, diphenoxylate/atropine, and sometimes chlordiazepoxide. Patients were also ...Delusional infestation (DI) is a psychocutaneous condition in which patients exhibit a fixed, false belief that they are infested with an insect or a parasite despite evidence indicating the contrary. In this article, we present a case of DI presenting after the abrupt discontinuation of long-term use of the H1 antihistamine hydroxyzine.Aug 15, 2007 · Hydroxyzine (Vistaril) 25 to 100: 2: 3 to 7: 37 (9 to 21) Anticholinergic, CNS depression/stimulation: No: Antidepressants: ... Trazodone is the most commonly prescribed sleep aid, but there is ...

11802 n gessner rd houston tx 77064.

Jan 4, 2016 · Hydroxyzine was really similar to Trazodone for me. Unfortunately, because of some side effects with Trazodone, I had to stop taking it – but Hydroxyzine honestly feels very similar. Trazodone, in my experience, had a higher sedative effect for helping with sleep- but hydroxyzine’s anxiolytic (anti-anxiety) effect has been greater. Hydroxyzine has an average rating of 5.7 out of 10 from a total of 1375 ratings on Drugs.com. 46% of reviewers reported a positive effect, while 36% reported a negative effect. Mirtazapine has an average rating of 6.8 out of 10 from a total of 2023 ratings on Drugs.com. 56% of reviewers reported a positive effect, while 21% reported a negative ...Side Effects of Trazodone. Nausea, vomiting, and diarrhea or constipation. Dizziness, unsteadiness, dry mouth, and/or headache. Fatigue, tingling or numbness in the extremities (arms and legs), or ringing in the ears. Muscle pain, rash, tremors or shaking (mostly in the hands)SSRI with trazodone. Trazodone is a dual 5-HT 2A antagonist and serotonin reuptake inhibitor. Its 5-HT 2A blockade is believed to reduce the side-effects associated with the stimulation of 5-HT 2A, including sexual dysfunction, insomnia and anxiety. Trazodone has been largely used more for its sedative than its antidepressant properties.A 2001 study found that trazodone may help with insomnia and nightmares associated with post-traumatic stress disorder. Another possible benefit to taking trazodone for anxiety may be that you ...Doxepin has an average rating of 6.1 out of 10 from a total of 430 ratings on Drugs.com. 52% of reviewers reported a positive effect, while 35% reported a negative effect. Hydroxyzine has an average rating of 5.7 out of 10 from a total of 1375 ratings on Drugs.com. 46% of reviewers reported a positive effect, while 36% reported a negative effect.

Please know that the combination of trazodone and hydroxyzine can cause harmful interactions, including sedation, dizziness, and drowsiness, leading to the increased likelihood of falls, cognitive impairment, and other similar issues. Hydroxyzine was found to block peak hERG channel tail currents in a concentration‐dependent manner, with an IC 50 of 0.39 μmol/L at near‐physiological temperature (n = 4; Fig. 1). Inhibitory effects of hydroxyzine were also observed for specific voltage‐gated sodium and calcium cardiac ion channels (Nav1.5 and Cav1.2; Fig. 1). …Mar 1, 2011 · Many physicians prescribe hypnotics for hospitalized patients with insomnia. Frequently used medications include temazepam, diphenhydramine, quetiapine, and trazodone. We have found hydroxyzine, 25 mg to 100 mg nightly, to be effective in adults and geriatric patients and feel it is a more rational choice. Temazepam and other benzodiazepines ... Drug interactions are reported among people who take Hydroxyzine and Effexor. Common interactions among females include chronic kidney disease and constipation. Common interactions among males include pain and nausea. The phase IV clinical study analyzes what interactions people have when they take Hydroxyzine and Effexor together.Diphenhydramine and hydroxyzine are considered the drug of choice during pregnancy; however, it should be acknowledged that there are few studies in humans to confirm their …Applies to: trazodone. Alcohol can increase the nervous system side effects of traZODone such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with traZODone.Atypical antidepressants are safe for most people. However, in some circumstances they can cause problems. For example: Bupropion should not be used by people who have a seizure disorder or an eating disorder such as bulimia or anorexia.; Esketamine can cause serious side effects and must be administered by a psychiatrist …Sep 26, 2023 · Taking trazodone and St. John’s wort may lead to serotonin syndrome. It can also make trazodone less effective. Trazodone oral tablet may interact with valerian (also called valerian root). This herb is used to help with sleep. Taking trazodone and using valerian may lead to fatigue (low energy) and sleepiness. a seizure (convulsions). Side effects such as drowsiness and confusion may be more likely in older adults. Common hydroxyzine side effects may include: drowsiness; headache; dry mouth; or. skin rash. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.More about Vistaril ( hydroxyzine ) Ratings & Reviews. Trazodone has an average rating of 6.3 out of 10 from a total of 1410 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 31% reported a negative effect. Vistaril has an average rating of 5.6 out of 10 from a total of 233 ratings on Drugs.com. 45% of reviewers reported ...18 Oct 2021 ... In this episode, I discuss a medication known as hydroxyzine (Vistaril) ... How To Use HYDROXYZINE (VISTARIL). 23K views ... TRAZODONE FOR INSOMNIA | ...Trazadone and Hydroxyzine . I have been dealing with insomnia for a really long time and was prescribed hydroxyzine (50mg), but it did nothing for me, so my doctor prescribed me Tradazone (50mg) and it didn’t work either. ... i'm on 100mg of trazodone. that's been my dose over a year now. always works for me.

Gabapentin is an anticonvulsive medication that is primarily used to treat seizures and nerve pain. It was initially developed as a muscle relaxer and anti-spasmodic medication, but its anticonvulsive properties were discovered later. Gabapentin is also used as an adjunct to more potent anticonvulsants and for the management of certain types of ...

The uncontrolled medications prescribed in this sample were amitriptyline, doxepin, hydroxyzine, low-dose quetiapine, and trazodone. The controlled medications identified were clonazepam and lorazepam, … Trazodone produces transient improvement in sleep quality and sleep continuity in older patients with insomnia, but carries significant risks such as orthostatic hypotension and priapism [73,74]. For sleep-onset problem, melatonin, and synthetic melatonin agonists are the preferred therapeutic agents in older adults with insomnia [ 75 , 76 ]. difficulty with swallowing. dizziness. fainting. fast heartbeat. hives, itching, or skin rash. irregular or slow heart rate. puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue. trouble breathing. unusual tiredness or weakness.Gabapentin, also known аs Neurontin, is an anticonvulsant medication used to treat seizures and nerve pain. It works by affecting chemicals and nerves in the body. Gabapentin is available in various forms, including oral solution, cаpsules, and extended-release tablets.Interaction Details. Co-administration of Valium (diazepam) and hydroxyzine can potentiate the CNS (central nervous system) effects (e.g., increased sedation or respiratory depression) of either agent. Caution is recommended with this combination. If used together, you may feel drowsy or more tired when taking these …Hydroxyzine made me very groggy. So my doc prescribed Trazodone which works fine with me. To address bedtime anxiety, suggest trying Cognitive Behavioral Therapy - Insomnia and Sleep Hypnotherapy. My experience is, CBT-i helps reduce bedtime anxiety and Sleep Hypnotherapy helps falling asleep quickly and Trazodone helps keeping me …Wanna go to sleep and simply calm mast cells, go with hydroxyzine. Trazodone gave me akathisia, depression, and anger issues the next day. Also, hydroxyzine isn’t addictive. I’ve stopped taking it 4 times and come back to whenever I wish. Trazodone is harder to stop if you’ve been taking it a long time, and each time I would take it again ...Hydroxyzine. 10mg; 25mg; 50mg; Overview. Hydroxyzine Hydrochloride is an antihistamine, a medication known for preventing allergic reactions. However, its calming effects can be helpful in treating insomnia as well. ... Trazodone is an antidepressant that restores levels of serotonin in the brain. Research has shown it can be an effective ...Trazodone and Seroquel can be taken together if prescribed by the healthcare provider. Research on their concomitant use is limited but Seroquel is often prescribed with antidepressants like trazodone. Trazodone, an antidepressant, is categorized as a serotonin antagonist and reuptake inhibitor (SARI). It is primarily used for major depressive ...The usual hydroxyzine dose for adults with sleep problems is 50 mg per day, administered 30 minutes before bedtime. For doxylamine, the typical dose for insomnia is 25 mg per day, also taken 30 minutes before bed. Hydroxyzine and doxylamine haven’t been tested for long-term use in cases of insomnia.

Lauren boebert husband theater.

Harry potter andromeda.

The usual hydroxyzine dose for adults with sleep problems is 50 mg per day, administered 30 minutes before bedtime. For doxylamine, the typical dose for insomnia is 25 mg per day, also taken 30 minutes before bed. Hydroxyzine and doxylamine haven’t been tested for long-term use in cases of insomnia.Patients were excluded if requiring concomitant medication with the exception of trazodone, mirtazapine, or hydroxyzine 25 mg. All patients were on SSRI therapy for a minimum of 2 months (n = 9 on sertraline, n = 8 on fluoxetine, n = 8 on escitalopram, n = 7 on citalopram, and n = 4 on paroxetine).Hydroxyzine has an average rating of 5.7 out of 10 from a total of 1375 ratings on Drugs.com. 46% of reviewers reported a positive effect, while 36% reported a negative effect. Mirtazapine has an average rating of 6.8 out of 10 from a total of 2023 ratings on Drugs.com. 56% of reviewers reported a positive effect, while 21% reported a negative ...Experiences with trazadone/hydroxyzine? So a couple days ago I was prescribed these meds, 50mg trazadone every night and 25mg hydroxyzine as needed, like when I have anxiety attacks and/or flashbacks, or when I am overwhelmed for whatever reason. So far both have made me incredibly groggy and sleepy.Trazodone, sold under many brand names, is an antidepressant medication. It is used to treat major depressive disorder, anxiety disorders, and insomnia.Gabapentin, also known аs Neurontin, is an anticonvulsant medication used to treat seizures and nerve pain. It works by affecting chemicals and nerves in the body. Gabapentin is available in various forms, including oral solution, cаpsules, and extended-release tablets.Conclusion · Hydroxyzine and trazodone can potentially interact with each other and cause adverse effects. · Combining these medications can increase the risk .....DWF is a secure file format developed by Autodesk. The file format was created to improve the efficiency, distribution and communication of rich design data for users of print des... ….

OBJECTIVE: While trazodone is approved for the treatment of depression, the off-label use of this medication for insomnia has surpassed its usage as an antidepressant. In this systematic review, we examined the evidence for the efficacy and safety of trazodone for insomnia. METHODS: A literature search was conducted using MEDLINE/PubMed ...Dry mouth, headache, constipation, diarrhea, and sexual dysfunction. Trazodone may cause a discontinuation syndrome if abruptly stopped, symptoms include anxiety, agitation, and sleep disturbances. When the time comes to withdraw trazodone, the dosage should be tapered off slowly under a doctor's advice.traZODone venlafaxine. Applies to: trazodone and Effexor (venlafaxine) Using traZODone together with venlafaxine can increase the risk of a rare but serious condition called the serotonin syndrome, which may include symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive ...Hydroxyzine is used to help control anxiety and tension caused by nervous and emotional conditions. It can also be used to help control anxiety and produce sleep before surgery. ... Trazodone Triclabendazole Trimipramine Triptorelin Vandetanib Vardenafil Vemurafenib Venlafaxine Vilanterol Vinflunine Voclosporin Voriconazole Vorinostat Zolpidem ...Please know that the combination of trazodone and hydroxyzine can cause harmful interactions, including sedation, dizziness, and drowsiness, leading to the increased likelihood of falls, cognitive impairment, and other similar issues. These drugs can also cause adverse effects such as dry mouth, blurred vision, irregular heartbeats, and ...Lexapro (escitalopram) is an SSRI which can help treat symptoms of depression and anxiety disorders. Trazodone is an antidepressant of class serotonin-antagonist and reuptake inhibitors, which is approved to treat depression, sleep disorders, anxiety, fibromyalgia, etc. (2, 3) Trazodone can cause sedation, which helps manage insomnia and ...Apr 4, 2023 · Dry mouth, headache, constipation, diarrhea, and sexual dysfunction. Trazodone may cause a discontinuation syndrome if abruptly stopped, symptoms include anxiety, agitation, and sleep disturbances. When the time comes to withdraw trazodone, the dosage should be tapered off slowly under a doctor's advice. Hydroxyzine was found to block peak hERG channel tail currents in a concentration‐dependent manner, with an IC 50 of 0.39 μmol/L at near‐physiological temperature (n = 4; Fig. 1). Inhibitory effects of hydroxyzine were also observed for specific voltage‐gated sodium and calcium cardiac ion channels (Nav1.5 and Cav1.2; Fig. 1). These ...Trazodone is a prescription drug used to treat depression and sleep disorders like insomnia.When using trazodone for sleep, the drug is given at low doses—typically between 25 to 100 milligram (mg)—which reduces the risk of drug tolerance and daytime sleepiness. For some people, even lower doses may prove … Hydroxyzine and trazodone, The Autograph Collection's newest hotel in Greece is the Domes of Corfu, a family-friendly property bookable for 50,000 points per standard award night. Marriott has added a new pr..., Get ratings and reviews for the top 11 pest companies in Caseyville, IL. Helping you find the best pest companies for the job. Expert Advice On Improving Your Home All Projects Fea..., chlordiazePOXIDE hydrOXYzine. Applies to: chlordiazepoxide and Vistaril (hydroxyzine) Using chlordiazePOXIDE together with hydrOXYzine may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination., Diphenhydramine and hydroxyzine are considered the drug of choice during pregnancy; however, it should be acknowledged that there are few studies in humans to confirm their …, 14-C Urea breath test: Drug information; Abacavir and lamivudine: Drug information; Abacavir, lamivudine, and zidovudine: Drug information; Abacavir: Drug information, Hydroxyzine has an average rating of 5.7 out of 10 from a total of 1375 ratings on Drugs.com. 46% of reviewers reported a positive effect, while 36% reported a negative effect. Mirtazapine has an average rating of 6.8 out of 10 from a total of 2023 ratings on Drugs.com. 56% of reviewers reported a positive effect, while 21% reported a negative ..., Professional. Interactions between your drugs. Moderate. traZODone hydrOXYzine. Applies to: trazodone and hydroxyzine. Using traZODone together with hydrOXYzine can increase the risk of an irregular heart rhythm that may be serious and potentially life-threatening, although it is a rare side effect., Trazodone is an antidepressant medication commonly prescribed off-label for insomnia, with typical initial dosing at 25–100 mg before bedtime. In depressed patients, 150 mg is often the initial nocturnal dose. The dosage used in depression can be titrated upward, even up to 600 mg nightly, while closely observing blood pressure., Trazodone is an antidepressant medication commonly prescribed off-label for insomnia, with typical initial dosing at 25–100 mg before bedtime. In depressed patients, 150 mg is often the initial nocturnal dose. The dosage used in depression can be titrated upward, even up to 600 mg nightly, while closely observing blood pressure., Trazodone, Oral Tablet. Trazodone is a generic drug that doctors may prescribe to treat depression. Side effects are usually mild, but possible serious side effects include rapid heart rate ..., Women are more comfortable approaching these stations. Female police officers in India are changing the way violence against women is reported. Opening all-woman police stations (W..., 5 Feb 2019 ... HYDROXYZINE (ATARAX) ... hydroxyzine high, hydroxyzine recreational use, hydroxyzine withdrawal ... TRAZODONE (DESYREL) - PHARMACIST REVIEW - #44., Trazodone, in particular, is frequently preferred and used in psychiatric practice. Its efficacy has mainly been demonstrated in adults with psychiatric disorders (Table 1). Trazodone is a 5-HT2A/C antagonist and is one of the most sedating antidepressants with significant morning hangover effect., Trazodone tablets come as 50mg, 100mg and 150mg strengths. Capsules come as 50mg and 100mg strengths. The liquid has either 10mg or 20mg of trazodone in every 1ml. For depression, the usual dose is 150mg daily. But in some cases your doctor may start you on a lower dose of 100mg to reduce the chance of side effects., Hydroxyzine is used to help control anxiety and tension caused by nervous and emotional conditions. It can also be used to help control anxiety and produce sleep before surgery. ... Trazodone Triclabendazole Trimipramine Triptorelin Vandetanib Vardenafil Vemurafenib Venlafaxine Vilanterol Vinflunine Voclosporin Voriconazole Vorinostat Zolpidem ..., For treating anxiety, you’ll likely start with a total daily dosage of 50 mg to 100 mg of hydroxyzine, taken in divided doses. This means you’ll take 12.5-mg to 25-mg doses two to four times ..., Using hydrOXYzine together with methocarbamol may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. You should avoid or limit the use of alcohol while being treated with these medications ..., Trazodone and Seroquel can be taken together if prescribed by the healthcare provider. Research on their concomitant use is limited but Seroquel is often prescribed with antidepressants like trazodone. Trazodone, an antidepressant, is categorized as a serotonin antagonist and reuptake inhibitor (SARI). It is primarily used for major depressive ..., Gabapentin is an anticonvulsive medication that is primarily used to treat seizures and nerve pain. It was initially developed as a muscle relaxer and anti-spasmodic medication, but its anticonvulsive properties were discovered later. Gabapentin is also used as an adjunct to more potent anticonvulsants and for the management of certain types of ..., 5 Feb 2019 ... HYDROXYZINE (ATARAX) ... hydroxyzine high, hydroxyzine recreational use, hydroxyzine withdrawal ... TRAZODONE (DESYREL) - PHARMACIST REVIEW - #44., Recently out of the blue I'm in a full blown anxiety driven mental breakdown. Doc prescribed hydroxyzine, which does seem to be helping. However, doc really wanted to start me on trazodone to address the issue long term. I'm very hesitant as I'm concerned about side effects. However, my main concern is feeling normal again and I'm not sure I'll ..., , Side Effects of Trazodone. Nausea, vomiting, and diarrhea or constipation. Dizziness, unsteadiness, dry mouth, and/or headache. Fatigue, tingling or numbness in the extremities (arms and legs), or ringing in the ears. Muscle pain, rash, tremors or shaking (mostly in the hands), Prescribing Guidelines for Pediatric Insomnia - Nationwide Children's ..., RESULTS: Evidence for the efficacy of trazodone has been repeatedly demonstrated for primary insomnia, as well as secondary insomnia, including for …, Hydroxyzine may be used to relieve anxiety or itching; however, it causes sedation so can affect a person's ability to drive or operate machinery. It should not be used during pregnancy or while breastfeeding unless the benefits outweigh the risks. 5. Tips. May be taken with or without food., Hydroxyzine is an antihistamine which treats allergies, but has the sleepy qualities like a night time cold over the counter medicine would have. The trazodone doesn’t knock me out, but makes it easier to fall asleep. I’ve used both to help insomnia/ sleep paralysis. 3. Reply. Share. SessionWitty534. • 3 yr. ago. , 1. How it works. Hydroxyzine may be used to relieve itch or as a premedication before surgery to relieve anxiety., Lexapro (escitalopram) is an SSRI which can help treat symptoms of depression and anxiety disorders. Trazodone is an antidepressant of class serotonin-antagonist and reuptake inhibitors, which is approved to treat depression, sleep disorders, anxiety, fibromyalgia, etc. (2, 3) Trazodone can cause sedation, which helps manage insomnia and ..., In a poll, Aircall's Senior Director of Sales Development learned 71% of participants felt fatigued. Here's how he still keeps his team productive anyway. Trusted by business build..., Yes the grogginess do subside within a few days. I took hydroxyzine and had the same feeling but went away within 2 days. If grogginess do continue overtime, you can try taking it earlier at night (around 7-8pm). Tyrese. Or as masso said; perhaps you need a dose adjustment., Recently out of the blue I'm in a full blown anxiety driven mental breakdown. Doc prescribed hydroxyzine, which does seem to be helping. However, doc really wanted to start me on trazodone to address the issue long term. I'm very hesitant as I'm concerned about side effects. However, my main concern is feeling normal again and I'm not sure I'll ..., Trazodone Vs. Benadryl For Dogs. Trazodone and Benadryl are both commonly used medications for dogs, but they have different purposes. Trazodone is primarily used for anxiety and behavioral issues, while Benadryl is an antihistamine that can help with allergies and itching. If your dog is experiencing anxiety, Trazodone may be a …